You will notice no difference here now that Google Chrome blocks annoying ads
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We never have used pop-ups, pop-unders, pop-overs, autoplay audio ads, or any of the other type of ads that take over the screen to one degree or another. Particularly infuriating are the pop-up/over ads that have an "X" that makes you think you are getting rid of it, but in fact you are clicking on it.
Forsaking such annoying ads had its cost since they were the most lucrative. That's a point I made during our semi-annual fundraisers in explaining the importance of reader donations. (See what I did there?)